Description

Methyl 6-Amino-4-Chloronicotinate is a high-purity, multi-functional organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its versatile molecular scaffold, which serves as a critical building block for the development of complex, high-value molecules. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the chloronicotinate moiety for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and photoactive compounds due to its conjugated pyridine structure.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Methyl 6-Amino-4-Chloronicotinate
CAS No.	1260666-60-1
Molecular Formula	C7H7ClN2O2
Molecular Weight	186.60 g/mol
Synonyms	Methyl 6-Amino-4-chloropyridine-3-carboxylate; 4-Chloro-6-aminonicotinic Acid Methyl Ester; 3-Pyridinecarboxylic acid, 6-amino-4-chloro-, methyl ester; 6-Amino-4-chloronicotinic acid methyl ester; Methyl 4-chloro-6-aminonicotinate
EINECS	Contact for details

Quality Control

Our Methyl 6-Amino-4-Chloronicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.