Description

6-Bromo-3-Chloro-Pyrazine-2-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its value lies in its unique halogenated pyrazine structure, which serves as a versatile precursor for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated heterocycle for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers, due to the electron-deficient pyrazine core.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and Industrial R&D: Fundamental building block in medicinal chemistry and process chemistry laboratories for scaffold diversification and structure-activity relationship (SAR) studies.

Basic Information

Product Name	6-Bromo-3-Chloro-Pyrazine-2-Carboxylic Acid
CAS No.	1260665-53-9
Molecular Formula	C5H2BrClN2O2
Molecular Weight	237.44 g/mol
Synonyms	3-Chloro-6-bromopyrazine-2-carboxylic acid; 2-Pyrazinecarboxylic acid, 6-bromo-3-chloro-; 6-Bromo-3-chloro-2-pyrazinecarboxylic acid; 6-Bromo-3-chloropyrazine-2-carboxylic acid; Bromochloro pyrazine carboxylic acid; BCPCA (abbreviation); (6-Bromo-3-chloro-pyrazin-2-yl)-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Chloro-Pyrazine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards, including cGMP (current Good Manufacturing Practice) for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area Percent)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.