Description

6-Chloro-3,4-Dihydro-2H-[2,7]Naphthyridin-1-One is a high-purity, advanced pharmaceutical intermediate with a fused heterocyclic structure, essential for modern medicinal chemistry research and development. This compound serves as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and scale-up of new drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug molecules, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop compounds with improved efficacy and selectivity.
• Chemical Synthesis: Serves as a versatile scaffold for further functionalization, enabling the creation of diverse chemical libraries for high-throughput screening.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the pharmaceutical industry in custom synthesis and process development.

Basic Information

Product Name	6-Chloro-3,4-Dihydro-2H-[2,7]Naphthyridin-1-One
CAS No.	1260664-25-2
Molecular Formula	C8H7ClN2O
Molecular Weight	182.61 g/mol
Synonyms	6-Chloro-1,2,3,4-tetrahydro-[2,7]naphthyridin-1-one; 6-Chloro-3,4-dihydro-2H-[2,7]naphthyridin-1(6H)-one; 6-Chloro-1,2,3,4-tetrahydro[2,7]naphthyridin-1-one; 6-Chloro-1-oxo-1,2,3,4-tetrahydro-[2,7]naphthyridine; 1260664-25-2; 6-Chloro-3,4-dihydro-2H-[2,7]naphthyridin-1-one
EINECS	Contact for details

Quality Control

Our 6-Chloro-3,4-Dihydro-2H-[2,7]Naphthyridin-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.