Description

5,6,7,8-Tetrahydro-[1,6]Naphthyridine-3-Carboxylic Acid is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization due to its privileged naphthyridine scaffold.
• Chemical Biology: Employed as a molecular probe or tag for studying biological pathways and protein interactions.
• Agrochemical Research: Serves as a building block for developing novel pesticides and herbicides with specific modes of action.
• Material Science: Potential precursor for the synthesis of specialty chemicals, ligands for catalysis, or organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and scale-up services for client projects.

Basic Information

Product Name	5,6,7,8-Tetrahydro-[1,6]Naphthyridine-3-Carboxylic Acid
CAS No.	1260664-02-5
Molecular Formula	C9H10N2O2
Molecular Weight	178.19 g/mol
Synonyms	5,6,7,8-Tetrahydro-1,6-naphthyridine-3-carboxylic acid; 3-Carboxy-5,6,7,8-tetrahydro-1,6-naphthyridine; 1,2,3,4-Tetrahydro-1,6-naphthyridine-8-carboxylic acid; THNCA; Tetrahydro[1,6]naphthyridine-3-carboxylic acid; 1260664-02-5; 5,6,7,8-Tetrahydro[1,6]naphthyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro-[1,6]Naphthyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.