Description

2-Bromo-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[1,5-A]Pyrazine CAS NO 1260663-45-3 is a high-purity, heterocyclic organic compound featuring a fused triazolopyrazine core with a bromine substituent. This molecule serves as a critical building block (advanced pharmaceutical intermediate) in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in developing new drug candidates, particularly in areas requiring complex nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to introduce bromine for further functionalization via cross-coupling reactions.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides and fungicides that leverage the triazolopyrazine scaffold.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways and target validation.
• Material Science Research: Investigated as a potential monomer or precursor for creating specialty polymers and advanced organic electronic materials.

Basic Information

Product Name	2-Bromo-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[1,5-A]Pyrazine
CAS No.	1260663-45-3
Molecular Formula	C6H7BrN4
Molecular Weight	215.05 g/mol
Synonyms	2-Bromo-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyrazine; 2-Bromo-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyrazine; 1260663-45-3; 2-Bromotetrahydrotriazolopyrazine; 2-Bromo-5,6,7,8-tetrahydro-1,2,4-triazolo[1,5-a]pyrazine; 2-Bromo-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyrazine; 2-Bromo-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyrazine; 2-Bromo-5,6,7,8-tetrahydrotriazolopyrazine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[1,5-A]Pyrazine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.