Description

Pyridin-4-Yl-Glycine tert-Butyl Ester is a high-purity, protected amino acid derivative featuring a pyridine heterocycle. This compound is a critical pharmaceutical intermediate and building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and peptide mimetics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Peptidomimetic Synthesis: Used to incorporate a pyridyl-glycine moiety into peptide backbones to enhance stability, bioavailability, and receptor binding affinity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probes: Employed in the development of labeled compounds and probes for studying biological pathways and enzyme functions.
• Agrochemical Research: Potential intermediate in the development of novel herbicides or plant growth regulators.

Basic Information

Product Name	Pyridin-4-Yl-Glycine tert-Butyl Ester
CAS No.	1260640-33-2
Molecular Formula	C11H16N2O2
Molecular Weight	208.26 g/mol
Synonyms	4-Pyridylglycine tert-butyl ester; tert-Butyl 2-amino-2-(pyridin-4-yl)acetate; 2-Amino-2-(4-pyridinyl)acetic acid 1,1-dimethylethyl ester; Glycine, N-(4-pyridinyl)-, 1,1-dimethylethyl ester; Boc-4-Pyridylglycine-OtBu (common abbreviation); (4-Pyridyl)glycine tert-butyl ester; N-(Pyridin-4-yl)glycine tert-butyl ester
EINECS	Contact for details

Quality Control

Our Pyridin-4-Yl-Glycine tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.