Description

(3R,5R)-3,5-Dimethylpiperazin-2-One CAS NO 1260619-40-6 is a high-purity, stereochemically defined chiral piperazinone derivative, serving as a critical advanced pharmaceutical intermediate and building block in organic synthesis. Its defined stereochemistry is essential for constructing complex molecules with specific biological activity, making it invaluable for research and development. This compound is primarily required by pharmaceutical and biotechnology companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas like oncology and neurology.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a building block for constructing molecules with defined stereocenters in medicinal chemistry and process R&D.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in enantioselective transformations.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Peptidomimetics: Incorporated into the backbone of peptide-like structures to enhance metabolic stability and bioavailability.

Basic Information

Product Name	(3R,5R)-3,5-Dimethylpiperazin-2-One
CAS No.	1260619-40-6
Molecular Formula	C6H12N2O
Molecular Weight	128.17 g/mol
Synonyms	(3R,5R)-3,5-Dimethyl-2-piperazinone; (3R,5R)-3,5-Dimethylpiperazin-2-one; (3R,5R)-3,5-Dimethyl-3,4,5,6-tetrahydro-2H-pyrazin-2-one; (3R,5R)-3,5-Dimethyl-2-oxopiperazine; (3R,5R)-3,5-Dimethyl-2-piperazinone; (3R,5R)-3,5-Dimethyl-2-piperazinone; (R,R)-3,5-Dimethylpiperazin-2-one; (R,R)-3,5-Dimethyl-2-piperazinone
EINECS	Contact for details

Quality Control

Our (3R,5R)-3,5-Dimethylpiperazin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee batch-to-batch consistency and traceability for your R&D and cGMP manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.