Description

Piperazine, 2-Methyl-4-(4-Nitrophenyl)-1-(Phenylmethyl)-, (2R)- is a high-purity, chiral piperazine derivative of significant interest in advanced pharmaceutical synthesis. This compound serves as a critical chiral building block or intermediate for the development of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the discovery and process development of enantiomerically pure therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for neurological and psychiatric applications.
• API Synthesis: Used in the multi-step synthesis of complex, enantiomerically pure Active Pharmaceutical Ingredients (APIs).
• Asymmetric Catalysis Research: Serves as a ligand precursor or a model substrate in the development of new asymmetric catalytic processes.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Process Chemistry: Used in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	Piperazine, 2-Methyl-4-(4-Nitrophenyl)-1-(Phenylmethyl)-, (2R)-
CAS No.	1260608-48-7
Molecular Formula	C18H21N3O2
Molecular Weight	311.38 g/mol
Synonyms	(2R)-2-Methyl-4-(4-nitrophenyl)-1-(phenylmethyl)piperazine; (R)-2-Methyl-4-(4-nitrophenyl)-1-benzylpiperazine; 1-Benzyl-2-methyl-4-(4-nitrophenyl)piperazine, (R)-; UNII-Contact for details; 1260608-48-7; (R)-1-Benzyl-2-methyl-4-(4-nitrophenyl)piperazine; (2R)-1-Benzyl-2-methyl-4-(4-nitrophenyl)piperazine
EINECS	Contact for details

Quality Control

Our Piperazine, 2-Methyl-4-(4-Nitrophenyl)-1-(Phenylmethyl)-, (2R)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.