Description

6-Bromo-1H-Pyrrolo[3,2-B]Pyridine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated fused heterocyclic structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug molecules, particularly in oncology and anti-inflammatory research.
• Kinase Inhibitor Development: Serves as a core scaffold for designing and optimizing potent and selective kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns.
• Chemical Biology Probes: Employed in the creation of molecular probes to study specific biological pathways and protein functions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.
• Agrochemical Research: Potential application in the discovery of new active ingredients for crop protection.

Basic Information

Product Name	6-Bromo-1H-Pyrrolo[3,2-B]Pyridine-2-Carboxylic Acid
CAS No.	1260386-47-7
Molecular Formula	C8H5BrN2O2
Molecular Weight	241.04 g/mol
Synonyms	6-Bromo-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid; 6-Bromo-2-carboxy-1H-pyrrolo[3,2-b]pyridine; 1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid, 6-bromo-; 6-Bromo-1H-7-azaindole-2-carboxylic acid; 6-Bromo-7-azaindole-2-carboxylic acid; 6-Bromo-2-carboxy-7-azaindole; 6-Bromo-2-carboxy-1H-pyrrolo[3,2-b]pyridine
EINECS	Contact for details

Quality Control

Our production of 6-Bromo-1H-Pyrrolo[3,2-B]Pyridine-2-Carboxylic Acid adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if possible. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.