Description

6-Chloro-3-Cyano-5-Azaindole is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its role as a key synthon in the development of novel kinase inhibitors and other biologically active molecules. Pharmaceutical R&D and fine chemical synthesis companies need it for constructing complex molecular architectures in drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of protein kinase inhibitors targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new active ingredients with specific biological activity.
• Organic Synthesis: Serves as a versatile precursor for constructing complex nitrogen-containing heterocycles via further functionalization.
• Biochemical Tool Compound Development: Employed in creating probes for studying enzymatic pathways and cellular signaling.
• Material Science Research: Investigated as a component for organic electronic materials due to its conjugated azaindole core.

Basic Information

Product Name	6-Chloro-3-Cyano-5-Azaindole
CAS No.	1260381-90-5
Molecular Formula	C8H4ClN3
Molecular Weight	177.59 g/mol
Synonyms	6-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile; 6-Chloro-3-cyano-1H-pyrrolo[2,3-b]pyridine; 6-Chloro-3-cyano-7-azaindole; 6-Chloro-3-cyano-1H-7-azaindole; 6-Chloro-3-cyano-5-aza-indole; 1H-Pyrrolo[2,3-b]pyridine-3-carbonitrile, 6-chloro-
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Cyano-5-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.