Description

2H-Pyrrolo[3,2-B]Pyridin-2-One,1,3-Dihydro-6-Iodo- is a high-value iodinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key precursor for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of potential drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Agrochemical Development: Employed as a building block for novel active ingredients in crop protection products.
• Material Science: Potential precursor for organic electronic materials or metal-organic frameworks (MOFs) due to its fused heterocyclic structure.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Chemical Biology Probes: Used in the development of molecular probes and tags for studying biological systems.

Basic Information

Product Name	2H-Pyrrolo[3,2-B]Pyridin-2-One,1,3-Dihydro-6-Iodo-
CAS No.	1260381-60-9
Molecular Formula	C7H5IN2O
Molecular Weight	260.03 g/mol
Synonyms	6-Iodo-1,3-dihydro-2H-pyrrolo[3,2-b]pyridin-2-one; 1,3-Dihydro-6-iodo-2H-pyrrolo[3,2-b]pyridin-2-one; 6-Iodo-2H-pyrrolo[3,2-b]pyridin-2-one; 6-Iodopyrrolo[3,2-b]pyridin-2(1H)-one; 1260381-60-9; AI3-72431; ZINC000103223511; AKOS040759090; FT-0770739; SCHEMBL24243411
EINECS	Contact for details

Quality Control

Our 2H-Pyrrolo[3,2-B]Pyridin-2-One,1,3-Dihydro-6-Iodo- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.