Description

2-Bromo-3-Methylisonicotinonitrile is a versatile and high-value brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure makes it an essential intermediate for the development of complex pharmaceuticals, agrochemicals, and functional materials. This compound is particularly sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science: Serves as a building block for creating functional organic materials, such as ligands for catalysts and components for organic electronics.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce functionalized pyridine motifs into more complex molecular architectures.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and exploratory research in academic institutions and CROs (Contract Research Organizations).

Basic Information

Product Name	2-Bromo-3-Methylisonicotinonitrile
CAS No.	1260024-26-7
Molecular Formula	C7H5BrN2
Molecular Weight	197.04 g/mol
Synonyms	3-Methyl-2-bromoisonicotinonitrile; 2-Bromo-3-methyl-4-cyanopyridine; 4-Pyridinecarbonitrile, 2-bromo-3-methyl-; Isonicotinonitrile, 2-bromo-3-methyl-; 2-Bromo-3-methylpyridine-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Methylisonicotinonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.