Description

6-(4-Chlorophenyl)Pyrazine-2-Carboxylic Acid is a high-value, functionalized pyrazine derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring both a chlorophenyl group and a carboxylic acid moiety, makes it an essential building block for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and pharmaceutical development teams engaged in the creation of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in developing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazine core.
• Ligand Synthesis: Serves as a starting material for creating chelating ligands in coordination chemistry and catalysis.
• Material Science: Building block for organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs), due to its conjugated system.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	6-(4-Chlorophenyl)Pyrazine-2-Carboxylic Acid
CAS No.	1258850-50-8
Molecular Formula	C11H7ClN2O2
Molecular Weight	234.64 g/mol
Synonyms	6-(4-Chlorophenyl)-2-pyrazinecarboxylic acid; 2-Pyrazinecarboxylic acid, 6-(4-chlorophenyl)-; 4-Chloro-α-pyrazinylbenzenecarboxylic acid; 6-(p-Chlorophenyl)pyrazine-2-carboxylic acid; (4-Chlorophenyl)pyrazinecarboxylic acid; CPCA (abbreviation); 1258850-50-8 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 6-(4-Chlorophenyl)Pyrazine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 98.0% / ≥ 99.0% (High Purity Grades)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.