Description

1-Boc-4-[2-[[1-(4,4-Dimethyl-2,6-Dioxocyclohexylidene)Ethyl]Amino]Ethyl]Piperazine is a sophisticated heterocyclic building block featuring a protected piperazine core and a dioxocyclohexylidene moiety. This compound is of significant value in pharmaceutical research and development, primarily serving as a key intermediate for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities. It is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, structurally complex intermediates for lead optimization and scale-up.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of protease inhibitors, kinase inhibitors, and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used in lead compound optimization and structure-activity relationship (SAR) studies due to its versatile reactive sites.
• Peptidomimetic Synthesis: Serves as a scaffold for constructing peptidomimetics and constrained peptide analogs.
• Chemical Biology Probes: Employed in the development of molecular probes and tools for studying biological pathways.
• Agrochemical Development: Potential intermediate in the synthesis of novel herbicides or fungicides.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP conditions.

Basic Information

Product Name	1-Boc-4-[2-[[1-(4,4-Dimethyl-2,6-Dioxocyclohexylidene)Ethyl]Amino]Ethyl]Piperazine
CAS No.	1258652-71-9
Molecular Formula	C21H35N3O5
Molecular Weight	409.52 g/mol
Synonyms	1-Boc-4-(2-((1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl)amino)ethyl)piperazine; tert-Butyl 4-[2-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]amino]ethyl]piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-[2-[[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]amino]ethyl]piperazine; N-Boc-4-(2-((1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl)amino)ethyl)piperazine; Piperazine, 1-(1,1-dimethylethoxy)carbonyl-4-[2-[[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]amino]ethyl]-; BOC-DMDP-Piperazine Derivative
EINECS	Contact for details

Quality Control

Our 1-Boc-4-[2-[[1-(4,4-Dimethyl-2,6-Dioxocyclohexylidene)Ethyl]Amino]Ethyl]Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure compliance with research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.