Description

n-(Prop-2-Yn-1-Yl)Piperazine-1-Sulfonamide Hydrochloride is a high-purity, specialized organic compound primarily used as a key intermediate in pharmaceutical research and development. Its value lies in its functionalized piperazine-sulfonamide scaffold, which is a privileged structure in medicinal chemistry for designing bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those focused on synthesizing novel drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential therapeutic agents, including kinase inhibitors and other small-molecule drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Academic Research: A valuable reagent for universities and research institutes conducting organic synthesis and drug discovery programs.

Basic Information

Product Name	n-(Prop-2-Yn-1-Yl)Piperazine-1-Sulfonamide Hydrochloride
CAS No.	1258640-72-0
Molecular Formula	C8H14ClN3O2S
Molecular Weight	251.73 g/mol
Synonyms	1-(Prop-2-yn-1-yl)piperazine-1-sulfonamide hydrochloride; N-(2-Propynyl)piperazine-1-sulfonamide hydrochloride; 1-(Prop-2-ynyl)piperazine-1-sulfonamide HCl; Piperazine-1-sulfonamide, 1-(2-propynyl)-, hydrochloride; 1258640-72-0; N-Propargylpiperazine-1-sulfonamide hydrochloride
EINECS	Contact for details

Quality Control

Our n-(Prop-2-Yn-1-Yl)Piperazine-1-Sulfonamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring the material meets the stringent requirements for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.