Description

tert-Butyl (6-Nitropyridin-2-Yl)Carbamate Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its nitropyridine and carbamate functional groups. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides due to its bioactive nitropyridine core.
• Chemical Synthesis: Serves as a protected amine derivative for further functionalization in multi-step organic syntheses.
• Academic & R&D: Employed in university and corporate research laboratories for method development and exploratory chemistry.
• API Manufacturing: Integrated into scaled-up production processes for final active pharmaceutical ingredients under controlled GMP environments.

Basic Information

Product Name	tert-Butyl (6-Nitropyridin-2-Yl)Carbamate Hydrochloride
CAS No.	1258640-05-9
Molecular Formula	C10H14N3O4 • HCl
Molecular Weight	277.70 g/mol (Free base: 241.24 g/mol)
Synonyms	Boc-6-Nitro-2-aminopyridine Hydrochloride; 2-((tert-Butoxycarbonyl)amino)-6-nitropyridine Hydrochloride; N-Boc-2-Amino-6-nitropyridine HCl; tert-Butyl N-(6-nitropyridin-2-yl)carbamate Hydrochloride; 6-Nitro-2-pyridinylcarbamic Acid 1,1-Dimethylethyl Ester Hydrochloride; 2-(Boc-amino)-6-nitropyridine Hydrochloride; (6-Nitro-pyridin-2-yl)-carbamic acid tert-butyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our tert-Butyl (6-Nitropyridin-2-Yl)Carbamate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.