Description

5,5-Difluoro-Piperidin-3-Ol is a high-purity, fluorinated piperidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique chemical structure, which introduces both fluorine atoms and a hydroxyl group onto the piperidine scaffold, enabling precise modulation of molecular properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, metabolic diseases, and oncology.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the difluoro moiety can enhance bioavailability and metabolic stability.
• Chemical Biology Probe: Serves as a versatile scaffold for constructing molecular probes to study enzyme function and biological pathways.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Precursor: Potential use in the synthesis of advanced polymers and functional materials with tailored properties.

Basic Information

Product Name	5,5-Difluoro-Piperidin-3-Ol
CAS No.	1258639-09-6
Molecular Formula	C5H9F2NO
Molecular Weight	137.13 g/mol
Synonyms	5,5-Difluoropiperidin-3-ol; 3-Hydroxy-5,5-difluoropiperidine; 5,5-Difluoro-3-hydroxypiperidine; 5,5-Difluoro-3-piperidinol; 3-Piperidinol, 5,5-difluoro-; 1258639-09-6
EINECS	Contact for details

Quality Control

Every batch of 5,5-Difluoro-Piperidin-3-Ol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up activities. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.