Description

3-(5-Aminopyridin-3-Yl)Benzonitrile is a high-purity aromatic nitrile derivative featuring a strategically positioned aminopyridine moiety. This compound serves as a versatile and critical pharmaceutical intermediate and organic building block for advanced chemical synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed coupling reactions and coordination chemistry.
• Material Science Research: Monomer or precursor for the synthesis of functional polymers, dyes, and advanced organic materials.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes and diagnostic agents.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects.

Basic Information

Product Name	3-(5-Aminopyridin-3-Yl)Benzonitrile
CAS No.	1258628-06-6
Molecular Formula	C12H9N3
Molecular Weight	195.22 g/mol
Synonyms	3-(5-Aminopyridin-3-yl)benzonitrile; 3-Cyano-3'-amino-1,1'-biphenyl; 3'-Amino-[1,1'-biphenyl]-3-carbonitrile; 5-(3-Cyanophenyl)pyridin-3-amine; 3-Pyridinamine, 5-(3-cyanophenyl)-; [1,1'-Biphenyl]-3-carbonitrile, 3'-amino-
EINECS	Contact for details

Quality Control

Our 3-(5-Aminopyridin-3-Yl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ICH Q7, and other relevant regulatory guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.