Description

Mpeg11-Br CAS NO 1258596-39-2 is a specialized monomethoxy polyethylene glycol (mPEG) derivative functionalized with a bromine (Br) group at the terminus of an 11-unit PEG spacer. This compound is a crucial bifunctional linker in advanced organic synthesis and bioconjugation, enabling the controlled attachment of molecules to surfaces, polymers, or biological entities. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing drug delivery systems, diagnostic agents, and functional polymers.

Application

• Pharmaceutical Conjugation: Acts as a heterobifunctional linker for attaching drugs, peptides, or imaging agents to carriers like nanoparticles or antibodies in ADC (Antibody-Drug Conjugate) development.
• Polymer & Material Science: Serves as a macro-initiator for Atom Transfer Radical Polymerization (ATRP) to create well-defined block copolymers and PEGylated surfaces.
• Bioconjugation & Probe Synthesis: Used to introduce PEG spacers and reactive bromine handles onto biomolecules (proteins, oligonucleotides) for further functionalization or labeling.
• Hydrogel & Biomaterial Fabrication: A key building block for synthesizing cross-linked PEG-based hydrogels with tailored degradation and release properties.
• Surface Modification: Employed to create functional, non-fouling coatings on medical devices, sensors, and implants via the reactive bromine end-group.
• Intermediate for Further Synthesis: The bromine group can be readily substituted to introduce other functionalities like amines, azides, or thiols, expanding its utility.

Basic Information

Product Name	Mpeg11-Br
CAS No.	1258596-39-2
Molecular Formula	C28H57BrO12
Molecular Weight	665.66 g/mol
Synonyms	mPEG11-Br; Bromo-PEG11-OMe; α-Methoxy-ω-bromo-undeca(ethylene glycol); 2,5,8,11,14,17,20,23,26,29,32-Undecaoxatetratetracontan-34-yl Bromide; 1-Bromo-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontan-35-ol, 35-Methoxy-; Poly(ethylene glycol) methyl ether bromo-terminated (MW ~550); Br-PEG11-OMe; Bromo-terminated monomethoxy polyethylene glycol (n=11)
EINECS	Contact for details

Quality Control

Our Mpeg11-Br is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and assay, NMR for structural confirmation, and mass spectrometry for molecular weight verification. We provide comprehensive Certificates of Analysis (COA) with detailed specifications for trace solvents, moisture content (Karl Fischer), and functional group analysis. Our quality commitment ensures batch-to-batch consistency for your critical R&D and cGMP-grade manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere, consider sealing under argon or nitrogen. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Molecular Weight (MS)	665.66 ± 5 Da
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Bromine Content	Theoretical ± 2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.