Description

4-Hydrazinyl-1-Piperidinecarboxylic Acid 1,1-Dimethylethyl Ester Hydrochloride is a high-purity, protected piperidine-hydrazine derivative used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and fine chemicals, where its reactive hydrazinyl group enables the construction of complex heterocyclic scaffolds. It is primarily targeted at the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of drug candidates, particularly those containing piperidine and hydrazine pharmacophores.
• Medicinal Chemistry Research: Used in the design and discovery of new chemical entities for various therapeutic targets.
• Agrochemical Synthesis: Serves as a precursor in the development of novel pesticides and herbicides.
• Heterocyclic Compound Library Synthesis: Employed in combinatorial chemistry to create diverse libraries of nitrogen-containing heterocycles for screening.
• Ligand and Catalyst Development: Useful for constructing complex ligands used in catalytic systems.
• Peptidomimetic Synthesis: Acts as a constrained amino acid surrogate in the design of peptide analogs.

Basic Information

Product Name	4-Hydrazinyl-1-Piperidinecarboxylic Acid 1,1-Dimethylethyl Ester Hydrochloride
CAS No.	1258001-18-1
Molecular Formula	C10H22ClN3O2
Molecular Weight	251.76 g/mol
Synonyms	tert-Butyl 4-hydrazinylpiperidine-1-carboxylate hydrochloride; 1-Boc-4-hydrazinopiperidine hydrochloride; 4-Hydrazino-1-piperidinecarboxylic acid tert-butyl ester hydrochloride; 1-(tert-Butoxycarbonyl)-4-hydrazinopiperidine hydrochloride; N-Boc-4-hydrazinopiperidine HCl; tert-Butyl 4-hydrozinylpiperidine-1-carboxylate hydrochloride; 4-Hydrazinylpiperidine-1-carboxylic acid tert-butyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Hydrazinyl-1-Piperidinecarboxylic Acid 1,1-Dimethylethyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.