Description

(R)-4-Boc-3-(2-Oxo-Ethyl)-Morpholine CAS NO 1257856-87-3 is a high-purity, chiral morpholine derivative used as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is essential for research and production in pharmaceutical, agrochemical, and specialty chemical industries where precise stereochemistry and functional group compatibility are paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of enantiomerically pure active ingredients for crop protection agents.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Employed in the design and synthesis of morpholine-based peptidomimetics for medicinal chemistry applications.
• Custom Chemical Synthesis: A versatile building block for contract research organizations (CROs) and CDMOs producing custom fine chemicals.
• Academic Research: Used in university and institutional labs for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(R)-4-Boc-3-(2-Oxo-Ethyl)-Morpholine
CAS No.	1257856-87-3
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	(R)-tert-Butyl 3-(2-oxoethyl)morpholine-4-carboxylate; (R)-4-(tert-Butoxycarbonyl)-3-(2-oxoethyl)morpholine; (R)-N-Boc-3-(2-Oxoethyl)morpholine; (3R)-4-[(1,1-Dimethylethoxy)carbonyl]-3-(2-oxoethyl)morpholine; (R)-3-(2-Oxoethyl)morpholine-4-carboxylic acid tert-butyl ester; BOC-(R)-3-(2-Oxoethyl)morpholine; (R)-Boc-Morpholine-3-acetaldehyde (protected form)
EINECS	Contact for details

Quality Control

Our (R)-4-Boc-3-(2-Oxo-Ethyl)-Morpholine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC to ensure enantiomeric purity and identity confirmation by NMR and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting purity, assay, and impurity profiles to meet the stringent requirements of pharmaceutical and advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep container tightly sealed in a desiccated environment after opening.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Chiral Purity (HPLC)	≥98.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.