Description

Pyrrolo[3,2-C]Pyridine-3-Ylamine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and building block. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates. It is primarily sought by R&D teams and process chemists in the pharmaceutical, biotechnology, and fine chemical industries for creating complex molecules with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new drug discovery programs.
• Kinase Inhibitor Development: Serves as a core scaffold for the design and synthesis of potential kinase inhibitors due to the privileged pyrrolopyridine structure.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological processes and target validation.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce the aminopyrrolopyridine moiety into more complex molecular architectures.
• Contract Research & Manufacturing (CRAM): Supplied to organizations offering custom synthesis and process development services.

Basic Information

Product Name	Pyrrolo[3,2-C]Pyridine-3-Ylamine Dihydrochloride
CAS No.	1257535-49-1
Molecular Formula	C7H9N3 · 2HCl
Molecular Weight	224.09 g/mol (for dihydrochloride salt)
Synonyms	3-Aminopyrrolo[3,2-c]pyridine dihydrochloride; 1H-Pyrrolo[3,2-c]pyridin-3-amine dihydrochloride; Pyrrolo[3,2-c]pyridin-3-amine hydrochloride (1:2); 3-Pyrrolo[3,2-c]pyridinylamine dihydrochloride; 1257535-49-1; 3-APPD hydrochloride
EINECS	Contact for details

Quality Control

Our Pyrrolo[3,2-C]Pyridine-3-Ylamine Dihydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP compliance for advanced intermediates, ensuring traceability and documentation for regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.