Description

(5-Chloro-3-Fluoropyridin-2-Yl)Methanamine Hydrochloride is a high-purity, halogenated pyridine derivative building block essential for advanced organic synthesis. This compound is a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular modifications. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of fluorinated and chlorinated pyridine motifs.
• Chemical Research & Development: Serves as a versatile precursor for creating novel ligands, catalysts, and functional materials in academic and industrial R&D laboratories.
• Ligand Synthesis: Employed in the preparation of specialized ligands for metal-organic frameworks (MOFs) or catalytic systems due to its amine functionality and halogen handles.
• Custom Synthesis Projects: A starting material for contract research organizations (CROs) and custom synthesis manufacturers producing specialized compounds for client-specific applications.

Basic Information

Product Name	(5-Chloro-3-Fluoropyridin-2-Yl)Methanamine Hydrochloride
CAS No.	1257535-29-7
Molecular Formula	C6H7Cl2FN2
Molecular Weight	205.04 g/mol
Synonyms	2-(Aminomethyl)-5-chloro-3-fluoropyridine hydrochloride; 1-(5-Chloro-3-fluoropyridin-2-yl)methanamine hydrochloride; (5-Chloro-3-fluoro-2-pyridinyl)methanamine hydrochloride; 5-Chloro-3-fluoro-2-pyridinemethanamine hydrochloride; 2-Pyridinemethanamine, 5-chloro-3-fluoro-, hydrochloride; (5-Chloro-3-fluoropyridin-2-yl)methylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (5-Chloro-3-Fluoropyridin-2-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.