Description

(6-Chloro-5-Fluoropyridin-3-Yl)Methanamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other targeted therapeutics. It is primarily needed by R&D laboratories, process development chemists, and manufacturers in the pharmaceutical and agrochemical industries seeking to build complex, functionalized heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of kinase inhibitors used in oncology and anti-inflammatory treatments.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and pesticides with specific modes of action.
• Chemical Biology: Used in the creation of molecular probes and tool compounds for studying biological pathways and target validation.
• Material Science: Potential monomer or precursor for creating specialized polymers and functional materials.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Product Name	(6-Chloro-5-Fluoropyridin-3-Yl)Methanamine Hydrochloride
CAS No.	1257535-10-6
Molecular Formula	C6H7Cl2FN2
Molecular Weight	209.04 g/mol
Synonyms	1-(6-Chloro-5-fluoropyridin-3-yl)methanamine hydrochloride; (6-Chloro-5-fluoro-3-pyridinyl)methanamine hydrochloride; 3-(Aminomethyl)-6-chloro-5-fluoropyridine hydrochloride; 5-Fluoro-6-chloro-3-pyridinemethanamine hydrochloride; 6-Chloro-5-fluoro-3-pyridinemethylamine hydrochloride; (6-Chloro-5-fluoropyridin-3-yl)methylamine hydrochloride; 3-(Aminomethyl)-5-fluoro-6-chloropyridine hydrochloride
EINECS	Contact for details

Quality Control

Our (6-Chloro-5-Fluoropyridin-3-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.