Description

3-(Benzyloxy)-6-Bromopyridin-2-Amine is a high-purity brominated pyridine derivative, a crucial building block in modern organic synthesis. Its value lies in its dual functionality, offering both a protected benzyloxy group and a reactive bromine atom for further cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides that require specific pyridine-based architectures.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom is amenable to Suzuki, Stille, and Buchwald-Hartwig amination reactions for carbon-carbon and carbon-nitrogen bond formation.
• Chemical Library Development: Employed in combinatorial and parallel synthesis to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	3-(Benzyloxy)-6-Bromopyridin-2-Amine
CAS No.	1257294-53-3
Molecular Formula	C₁₂H₁₁BrN₂O
Molecular Weight	279.13 g/mol
Synonyms	6-Bromo-3-(benzyloxy)pyridin-2-amine; 2-Amino-6-bromo-3-benzyloxypyridine; 3-Benzyloxy-6-bromopyridin-2-amine; 6-Bromo-3-(phenylmethoxy)-2-pyridinamine; 2-Pyridinamine, 6-bromo-3-(phenylmethoxy)-; 1257294-53-3
EINECS	Contact for details

Quality Control

Our 3-(Benzyloxy)-6-Bromopyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.