Description

tert-Butyl 4-(1,3-Dihydroxypropan-2-yl)piperidine-1-carboxylate is a high-purity, protected piperidine derivative featuring a Boc-protected amine and a diol functional group. This compound is a critical pharmaceutical intermediate and versatile organic building block for advanced synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Organic Synthesis Building Block: Used in medicinal chemistry for the construction of piperidine-containing scaffolds and chiral molecules.
• Ligand and Catalyst Development: Employed in the research and development of novel ligands for asymmetric catalysis and metal complexes.
• Peptidomimetics Research: Acts as a constrained scaffold in the design and synthesis of peptide mimics for drug discovery.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and enzyme functions.
• Academic and R&D Laboratories: A valuable reagent for method development and exploratory synthesis in organic chemistry.

Basic Information

Product Name	tert-Butyl 4-(1,3-Dihydroxypropan-2-yl)piperidine-1-carboxylate
CAS No.	1257294-03-3
Molecular Formula	C13H25NO4
Molecular Weight	259.34 g/mol
Synonyms	1-Boc-4-(1,3-dihydroxypropan-2-yl)piperidine; 1-(tert-Butoxycarbonyl)-4-(1,3-dihydroxypropan-2-yl)piperidine; tert-Butyl 4-(2,3-dihydroxypropyl)piperidine-1-carboxylate; 4-(1,3-Dihydroxypropan-2-yl)piperidine-1-carboxylic acid tert-butyl ester; 1-N-Boc-4-(1,3-dihydroxy-2-propyl)piperidine; BOC-4-(1,3-Dihydroxypropan-2-yl)piperidine; Piperidine-1-carboxylic acid, 4-(1,3-dihydroxy-2-propyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(1,3-Dihydroxypropan-2-yl)piperidine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.