Description

1,4-Di-tert-Butyl 2-(Aminomethyl)Piperazine-1,4-Dicarboxylate is a high-purity, functionalized piperazine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the construction of complex molecular architectures with precise stereochemistry and functionality. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty polymers where a protected aminomethyl piperazine core is required.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Preparation: Used in the synthesis of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Serves as a functional monomer or cross-linking agent for producing specialty polyamides, polyurethanes, and epoxy resins with tailored properties.
• Peptidomimetic Research: Integral component in the design and synthesis of peptide analogs and constrained scaffolds for biomedical research.
• Chemical Biology Probes: Utilized in the fabrication of molecular probes and linkers for studying biological pathways and protein interactions.

Basic Information

Product Name	1,4-Di-tert-Butyl 2-(Aminomethyl)Piperazine-1,4-Dicarboxylate
CAS No.	1256815-07-2
Molecular Formula	C15H29N3O4
Molecular Weight	315.41 g/mol
Synonyms	Di-tert-butyl 2-(aminomethyl)piperazine-1,4-dicarboxylate; 2-(Aminomethyl)-1,4-piperazinedicarboxylic acid 1,4-di-tert-butyl ester; 1,4-Bis(tert-butoxycarbonyl)-2-(aminomethyl)piperazine; Boc-Protected Aminomethylpiperazine; N-Boc-2-(Aminomethyl)piperazine; 1,4-Di-Boc-2-(aminomethyl)piperazine; tert-Butyl 2-(aminomethyl)piperazine-1,4-dicarboxylate
EINECS	Contact for details

Quality Control

Our 1,4-Di-tert-Butyl 2-(Aminomethyl)Piperazine-1,4-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring suitability for demanding pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.