Description

1-Phenyl-Piperazine-2-Carboxylic Acid Dihydrochloride is a high-purity, pharmaceutically relevant building block and intermediate. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Chemical Synthesis: Employed in the preparation of more complex piperazine-derived compounds for biological screening.

Basic Information

Product Name	1-Phenyl-Piperazine-2-Carboxylic Acid Dihydrochloride
CAS No.	1255717-01-1
Molecular Formula	C11H15N2O2 • 2HCl
Molecular Weight	279.17 g/mol (Free base: 207.26 g/mol)
Synonyms	1-Phenylpiperazine-2-carboxylic acid dihydrochloride; 2-Carboxy-1-phenylpiperazine dihydrochloride; 1-Phenyl-2-piperazinecarboxylic acid dihydrochloride; 1-Phenylpiperazine-2-carboxylic acid hydrochloride (1:2); (1-Phenylpiperazin-2-yl)carboxylic acid dihydrochloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical intermediates. Standard quality parameters include identity confirmation, purity assay, and impurity profiling. Certificates of Analysis (COA) detailing batch-specific results from advanced analytical techniques (HPLC, NMR) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.