Description

5,5-Difluoro-3-Piperidinecarboxylic Acid Methyl Ester is a high-purity, fluorinated piperidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique chemical structure, which introduces both fluorine atoms and a versatile ester functionality, enabling precise modifications to molecular scaffolds. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Synthesis: Used in the design and production of advanced pesticides and herbicides, where the difluorinated piperidine core can enhance biological activity and environmental stability.
• Chemical Biology Probe Development: Serves as a precursor for creating labeled compounds or molecular probes used in biochemical and pharmacological research.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials where fluorinated moieties impart desirable properties like chemical resistance or altered surface energy.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring a specific, fluorinated heterocyclic framework.

Basic Information

Product Name	5,5-Difluoro-3-Piperidinecarboxylic Acid Methyl Ester
CAS No.	1255667-31-2
Molecular Formula	C8H11F2NO2
Molecular Weight	191.18 g/mol
Synonyms	Methyl 5,5-difluoropiperidine-3-carboxylate; 3-Piperidinecarboxylic acid, 5,5-difluoro-, methyl ester; 5,5-Difluoropiperidine-3-carboxylic acid methyl ester; Methyl 5,5-difluoro-3-piperidinecarboxylate; Difluoropiperidine methyl ester; CAS 1255667-31-2
EINECS	Contact for details

Quality Control

Our 5,5-Difluoro-3-Piperidinecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.