Description

(2S,4S)-Methyl4-(Benzyloxycarbonylamino)Piperidine-2-Carboxylate is a high-purity, stereochemically defined piperidine derivative used as a critical chiral building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures with precise stereochemical control, which is essential for developing bioactive molecules. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and antiviral drugs.
• Peptidomimetic Synthesis: Serves as a constrained, non-natural amino acid analog for creating stable peptide mimics with enhanced pharmacological properties.
• Asymmetric Catalysis Ligand Precursor: Used in the preparation of chiral ligands and organocatalysts for enantioselective synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-protein interactions.
• Custom Synthesis Building Block: Provides a versatile scaffold for contract research organizations (CROs) and CDMOs performing custom synthesis for clients.
• Academic Research: Utilized in university and institutional labs for methodological development in organic chemistry and medicinal chemistry projects.

Basic Information

Product Name	(2S,4S)-Methyl4-(Benzyloxycarbonylamino)Piperidine-2-Carboxylate
CAS No.	1255664-48-2
Molecular Formula	C15H20N2O4
Molecular Weight	292.33 g/mol
Synonyms	(2S,4S)-Methyl 4-[(benzyloxy)carbonylamino]piperidine-2-carboxylate; (2S,4S)-1-Cbz-4-Amino-piperidine-2-carboxylic acid methyl ester; Methyl (2S,4S)-4-{[(benzyloxy)carbonyl]amino}piperidine-2-carboxylate; (2S,4S)-4-(Cbz-Amino)piperidine-2-carboxylic Acid Methyl Ester; (2S,4S)-4-[(Benzyloxycarbonyl)amino]piperidine-2-carboxylic acid methyl ester; (2S,4S)-N-Cbz-4-Aminopiperidine-2-carboxylic acid methyl ester; (2S,4S)-Piperidine-2-carboxylic acid, 4-[[(phenylmethoxy)carbonyl]amino]-, methyl ester
EINECS	Contact for details

Quality Control

Our (2S,4S)-Methyl4-(Benzyloxycarbonylamino)Piperidine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC to confirm stereochemical purity and identity, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available upon request. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.