Description

5'-Amino-2,3'-Bipyridine-3-Carbonitrile is a high-purity, multi-functional heterocyclic building block with significant synthetic utility. Its molecular structure, featuring both amino and nitrile functional groups on a bipyridine scaffold, makes it a versatile intermediate for constructing complex nitrogen-containing compounds. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry and material science. Its precise reactivity profile enables the synthesis of novel ligands, active pharmaceutical ingredients (APIs), and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic core.
• Ligand Synthesis: Serves as a building block for creating sophisticated chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of organic semiconductors, conductive polymers, and luminescent materials.
• Chemical Biology: Utilized as a probe or linker in bioconjugation chemistry and the development of biochemical tools.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	5'-Amino-2,3'-Bipyridine-3-Carbonitrile
CAS No.	1255634-62-8
Molecular Formula	C11H8N4
Molecular Weight	196.21 g/mol
Synonyms	3-Cyano-5'-amino-2,3'-bipyridine; 5'-Amino-[2,3']bipyridinyl-3-carbonitrile; 2,3'-Bipyridine-3-carbonitrile, 5'-amino-; 3-(5-Aminopyridin-2-yl)pyridine-2-carbonitrile; 5-Amino-2-(2-cyanopyridin-3-yl)pyridine; (5-Amino-2,3'-bipyridin-3-yl)methanenitrile; 5'-Amino-2,3'-dipyridyl-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 5'-Amino-2,3'-Bipyridine-3-Carbonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.