Description

5-(Trifluoromethyl)-2,3'-Bipyridin-5'-Amine is a high-purity, multi-functional bipyridine derivative featuring a reactive amine group and a trifluoromethyl substituent. This compound is a critical pharmaceutical intermediate and organic building block valued for its ability to modulate the physicochemical properties of target molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional ligands.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand in Catalysis: Serves as a precursor for constructing nitrogen-donor ligands used in transition metal catalysis for cross-coupling and other organic transformations.
• Material Science Research: Employed in the development of organic electronic materials, such as electron-transport layers or as a component in metal-organic frameworks (MOFs).
• Chemical Biology Probe: Useful for creating tagged molecules or affinity probes to study biological targets and pathways.
• Custom Synthesis & Contract Manufacturing: A versatile starting material for custom synthesis services catering to specialized chemical needs.

Basic Information

Product Name	5-(Trifluoromethyl)-2,3'-Bipyridin-5'-Amine
CAS No.	1255634-59-3
Molecular Formula	C11H8F3N3
Molecular Weight	239.20 g/mol
Synonyms	5'-Amino-5-(trifluoromethyl)-2,3'-bipyridine; 5-(Trifluoromethyl)-2,3'-bipyridin-5-amine; 2,3'-Bipyridin-5'-amine, 5-(trifluoromethyl)-; 5-(Trifluoromethyl)-[2,3']bipyridinyl-5'-ylamine; 5-Amino-5'-(trifluoromethyl)-2,3'-bipyridine
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-2,3'-Bipyridin-5'-Amine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.