Description

1-(2-Bromo-4-Chlorophenyl)Piperidin-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated aromatic structure. This compound is of significant value in modern organic synthesis, serving as a critical building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of complex molecules targeting various therapeutic and protective applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, leveraging its halogenated phenyl group.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the multi-step synthesis of complex APIs requiring a functionalized piperidinone moiety.
• Ligand and Catalyst Development: Potential use in creating specialized ligands for catalytic systems in asymmetric synthesis.

Basic Information

Product Name	1-(2-Bromo-4-Chlorophenyl)Piperidin-2-One
CAS No.	1255574-59-4
Molecular Formula	C11H11BrClNO
Molecular Weight	288.57 g/mol
Synonyms	2-Bromo-4-chloro-1-(2-oxopiperidin-1-yl)benzene; 1-(2-Bromo-4-chlorophenyl)-2-piperidinone; 2-Piperidinone, 1-(2-bromo-4-chlorophenyl)-; 1-(2-Bromo-4-chloro-phenyl)-piperidin-2-one; 1-(2-Bromo-4-chlorophenyl)azepan-2-one (tautomeric form); BCPPO; CAS 1255574-59-4
EINECS	Contact for details

Quality Control

Our 1-(2-Bromo-4-Chlorophenyl)Piperidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.