Description

6-(Chloromethyl)-N,1-Dimethyl-1H-Pyrazolo[3,4-D]-Pyrimidin-4-Amine is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents, particularly in kinase inhibitor research. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and process development. The precise functionalization offered by this molecule enables the targeted synthesis of complex bioactive compounds.

Application

This specialized chemical intermediate finds its primary utility in sophisticated research and development settings. Key application areas include:

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted therapeutic agents, especially protein kinase inhibitors.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a building block for creating tool compounds to study biological pathways and enzyme functions.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for active pharmaceutical ingredients (APIs).
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke molecules for clients.

Basic Information

Product Name	6-(Chloromethyl)-N,1-Dimethyl-1H-Pyrazolo[3,4-D]-Pyrimidin-4-Amine
CAS No.	1255147-44-4
Molecular Formula	C9H12ClN5
Molecular Weight	225.68 g/mol
Synonyms	6-(Chloromethyl)-N,1-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 6-(chloromethyl)-N,1-dimethyl-; 1255147-44-4; 6-(Chloromethyl)-N,1-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine; N,1-Dimethyl-6-(chloromethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our 6-(Chloromethyl)-N,1-Dimethyl-1H-Pyrazolo[3,4-D]-Pyrimidin-4-Amine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, it is recommended to keep the material at 2-8°C under an inert atmosphere. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.