Description

5-Chloro-2-[(2-Methylpyridin-3-Yl)Oxy]-Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. Its molecular structure makes it a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapeutic applications. This compound is essential for research and development chemists, process scale-up teams, and manufacturers in the global pharmaceutical and agrochemical industries seeking reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially for developing kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the research and development of new-generation herbicides and pesticides, leveraging its heterocyclic structure.
• Chemical Synthesis Building Block: Serves as a versatile synthon for constructing more complex pyridine and nicotinic acid derivatives in organic chemistry.
• Material Science Research: Investigated for potential use in creating functionalized ligands for catalysts or advanced organic materials.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for custom synthesis projects under cGMP guidelines.

Basic Information

Product Name	5-Chloro-2-[(2-Methylpyridin-3-Yl)Oxy]-Nicotinic Acid
CAS No.	1255147-31-9
Molecular Formula	C12H9ClN2O3
Molecular Weight	264.66 g/mol
Synonyms	5-Chloro-2-((2-methylpyridin-3-yl)oxy)nicotinic acid; 2-[(2-Methyl-3-pyridinyl)oxy]-5-chloro-3-pyridinecarboxylic acid; Nicotinic acid, 5-chloro-2-[(2-methyl-3-pyridinyl)oxy]-; 1255147-31-9; 5-Chloro-2-(2-methylpyridin-3-yloxy)nicotinic acid; 5-Chloro-2-[(2-methyl-3-pyridyl)oxy]nicotinic Acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-[(2-Methylpyridin-3-Yl)Oxy]-Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets exacting standards for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.