Description

tert-Butyl 2-Ethyl-5-Oxo-1,4-Diazepane-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the diazepane class of heterocyclic compounds. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, where precise chemical structure and reliable purity are paramount for successful outcomes.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of proprietary drug candidates, especially in medicinal chemistry research.
• API Synthesis: Used as a building block for constructing complex molecular frameworks found in potential treatments for neurological and psychiatric conditions.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale production for new chemical entities (NCEs).
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	tert-Butyl 2-Ethyl-5-Oxo-1,4-Diazepane-1-Carboxylate
CAS No.	1255147-08-0
Molecular Formula	C12H22N2O3
Molecular Weight	242.32 g/mol
Synonyms	1,4-Diazepane-1-carboxylic acid, 2-ethyl-5-oxo-, 1,1-dimethylethyl ester; 1-Boc-2-ethyl-5-oxo-1,4-diazepane; tert-Butyl 2-ethyl-5-oxoperhydro-1,4-diazepine-1-carboxylate; 2-Ethyl-5-oxo-1,4-diazepane-1-carboxylic acid tert-butyl ester; Boc-2-Et-5-oxo-1,4-diazepane
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Ethyl-5-Oxo-1,4-Diazepane-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.