Description

1-(Pyrazin-2-Yl)Cyclopropanamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a distinct cyclopropanamine-pyrazine hybrid structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for central nervous system (CNS) and anti-infective agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in the development and scale-up production of Active Pharmaceutical Ingredients (APIs) with cyclopropane and pyrazine motifs.
• Bioconjugation & Probe Development: The amine functionality allows for its use in creating chemical probes or conjugates for biochemical and diagnostic applications.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	1-(Pyrazin-2-Yl)Cyclopropanamine Hydrochloride
CAS No.	1255099-26-3
Molecular Formula	C7H10N3·HCl
Molecular Weight	171.63 g/mol (Free base: 135.18 g/mol)
Synonyms	1-(Pyrazin-2-yl)cyclopropan-1-amine hydrochloride; 1-(2-Pyrazinyl)cyclopropanamine hydrochloride; Cyclopropanamine, 1-(2-pyrazinyl)-, hydrochloride; 1-Aminocyclopropylpyrazine hydrochloride; 1-Cyclopropylaminopyrazine hydrochloride; 2-(1-Aminocyclopropyl)pyrazine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Pyrazin-2-Yl)Cyclopropanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.