Description

(1-(Pyridin-3-Yl)-3-(Trifluoromethyl)-1H-Pyrazol-5-Yl)Methanamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is valued for its unique heterocyclic structure, which incorporates a pyridine and a trifluoromethylated pyrazole, making it a critical building block in modern medicinal chemistry. It is primarily sought after by R&D teams and process chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in oncology, CNS, and anti-inflammatory research pipelines.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis due to its privileged heterocyclic motifs.
• Agrochemical Development: Serves as a building block for creating novel pesticides and herbicides, leveraging the biological activity of the pyrazole and pyridine rings.
• Chemical Biology Probes: Utilized in the development of molecular probes and tool compounds for target identification and validation in biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of client-specific molecules.

Basic Information

Product Name	(1-(Pyridin-3-Yl)-3-(Trifluoromethyl)-1H-Pyrazol-5-Yl)Methanamine Hydrochloride
CAS No.	1255041-98-5
Molecular Formula	C10H10ClF3N4
Molecular Weight	278.66 g/mol
Synonyms	1-(3-Pyridyl)-3-(trifluoromethyl)-1H-pyrazol-5-ylmethanamine hydrochloride; 5-(Aminomethyl)-1-(3-pyridinyl)-3-(trifluoromethyl)-1H-pyrazole hydrochloride; 1-(Pyridin-3-yl)-3-(trifluoromethyl)-1H-pyrazol-5-ylmethanamine HCl; (1-(3-Pyridyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl)methylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (1-(Pyridin-3-Yl)-3-(Trifluoromethyl)-1H-Pyrazol-5-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality commitment aligns with ICH guidelines, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.