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(R)-1-(3,5-Dichloropyridin-4-Yl)Ethanol CAS NO 1254473-68-1


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CAS No.:1254473-68-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(R)-1-(3,5-Dichloropyridin-4-Yl)Ethanol is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound matters because it provides a critical, enantiomerically pure building block for constructing complex molecules with defined stereochemistry. Pharmaceutical and agrochemical research organizations need it for the development of novel active ingredients, particularly where the specific (R)-configuration is required for biological activity.

Application

  • Pharmaceutical Intermediate: Key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and anti-infective therapies.
  • Agrochemical Synthesis: Used in creating enantiomerically pure active ingredients for next-generation herbicides, fungicides, and insecticides.
  • Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands used in asymmetric catalysis.
  • Chemical Research & Development: A valuable building block in academic and industrial labs for methodological studies and the synthesis of complex heterocyclic compounds.
  • Material Science: Potential intermediate for specialty polymers and functional materials requiring specific molecular architectures.

Basic Information

Product Name (R)-1-(3,5-Dichloropyridin-4-Yl)Ethanol
CAS No. 1254473-68-1
Molecular Formula C7H7Cl2NO
Molecular Weight 192.04 g/mol
Synonyms (R)-1-(3,5-Dichloro-4-pyridinyl)ethanol; (R)-1-(3,5-Dichloropyridin-4-yl)ethan-1-ol; (R)-α-(3,5-Dichloro-4-pyridyl)ethyl alcohol; (4R)-3,5-Dichloro-4-(1-hydroxyethyl)pyridine; (R)-3,5-Dichloro-4-(1-hydroxyethyl)pyridine; (R)-4-(1-Hydroxyethyl)-3,5-dichloropyridine; 1254473-68-1
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Quality Control

Our (R)-1-(3,5-Dichloropyridin-4-Yl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC to ensure high enantiomeric excess (ee) and identity confirmation by NMR and mass spectrometry. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, chiral purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, we recommend keeping the material at 2-8°C under an inert atmosphere to maintain stability and enantiomeric purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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