Description

4-Pyridinemethanol, 3,5-Dichloro-α-Methyl- CAS NO 1254473-66-9 is a high-purity, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile chiral intermediate, enabling the construction of complex molecular architectures with precise stereochemistry. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel therapeutic agents, particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Building block for creating advanced pesticides and herbicides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Used in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes and enzyme inhibitors in biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	4-Pyridinemethanol, 3,5-Dichloro-α-Methyl- CAS NO 1254473-66-9
CAS No.	1254473-66-9
Molecular Formula	C7H7Cl2NO
Molecular Weight	192.04 g/mol
Synonyms	(3,5-Dichloro-4-pyridinyl)methanol; α-Methyl-3,5-dichloro-4-pyridinemethanol; 3,5-Dichloro-4-(hydroxymethyl)pyridine; 4-(Hydroxymethyl)-3,5-dichloropyridine; 3,5-Dichloro-4-pyridylmethanol; (3,5-Dichloro-4-pyridyl)methanol; 3,5-Dichloro-pyridine-4-methanol
EINECS	Contact for details

Quality Control

Our 4-Pyridinemethanol, 3,5-Dichloro-α-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and chiral integrity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.