Description

1H-Pyrrolo[3,2-B]Pyridine-5-Carboxylic Acid, 2,3-Dihydro-, Methyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing next-generation drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing fused heterocyclic systems, enabling structure-activity relationship (SAR) studies.
• Research & Development (R&D): Essential for academic and industrial research focused on developing new pharmacophores and bioactive molecules.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for scale-up and cGMP production of clinical trial materials.
• Agrochemical Research: Potential application as an intermediate in the development of new agrochemicals with specific biological activity.
• Material Science: Investigated for use in creating organic electronic materials due to its conjugated π-system.

Basic Information

Product Name	1H-Pyrrolo[3,2-B]Pyridine-5-Carboxylic Acid, 2,3-Dihydro-, Methyl Ester
CAS No.	1254360-91-2
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	Methyl 2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-5-carboxylate; 1H-Pyrrolo[3,2-b]pyridine-5-carboxylic acid, 2,3-dihydro-, methyl ester; 2,3-Dihydro-1H-pyrrolo[3,2-b]pyridine-5-carboxylic acid methyl ester; Methyl 2,3-dihydro-1H-pyrrolo[3,2-b]pyridin-5-carboxylate; 5-(Methoxycarbonyl)-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrolo[3,2-B]Pyridine-5-Carboxylic Acid, 2,3-Dihydro-, Methyl Ester adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, and can support custom purity requirements for research or cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.