Description

Methyl 6-Chloro-5-Cyanopicolinate CAS NO 1254163-81-9 is a high-value, multi-functional heterocyclic building block and advanced pharmaceutical intermediate. Its molecular architecture, featuring a chlorinated and cyano-substituted picolinate ester, makes it a critical precursor in modern synthetic chemistry for constructing complex bioactive molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those targeting kinase inhibition and other enzymatic pathways.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Chemical Synthesis Building Block: Serves as a versatile precursor for further functionalization (e.g., hydrolysis, amidation, cross-coupling reactions) in fine chemical production.
• Material Science Research: Investigated as a monomer or functional additive for creating specialized polymers with unique electronic or photophysical properties.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new synthetic routes for heterocyclic compounds.

Basic Information

Product Name	Methyl 6-Chloro-5-Cyanopicolinate
CAS No.	1254163-81-9
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	Methyl 6-chloro-5-cyanopyridine-2-carboxylate; 6-Chloro-5-cyano-2-pyridinecarboxylic acid methyl ester; 2-Pyridinecarboxylic acid, 6-chloro-5-cyano-, methyl ester; Methyl 6-chloro-5-cyano-2-pyridinecarboxylate; 5-Cyano-6-chloropicolinic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 6-Chloro-5-Cyanopicolinate adheres to stringent in-process controls and final batch analysis to ensure consistent high purity and chemical identity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, impurity profile, and physical characteristics. We operate under a robust quality management system to guarantee reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.