Description

(2S)-2-Hydroxy-5-(Piperazin-1-Yl)Cyclopentanone is a high-purity chiral building block and advanced pharmaceutical intermediate of significant synthetic utility. Its unique structure, featuring both a piperazine moiety and a functionalized cyclopentanone ring, makes it a valuable scaffold for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). This compound is primarily targeted at research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective therapeutics.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to construct complex molecular architectures with defined chirality.
• Chemical Biology Probes: Can be functionalized to create molecular probes for studying biological pathways and enzyme interactions.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals and high-value compounds for various industrial research applications.

Basic Information

Item	Detail
Product Name	(2S)-2-Hydroxy-5-(Piperazin-1-Yl)Cyclopentanone
CAS No.	1253792-24-3
Molecular Formula	C9H16N2O2
Molecular Weight	184.24 g/mol
Synonyms	(2S)-5-(Piperazin-1-yl)cyclopentan-2-one; (2S)-5-(1-Piperazinyl)-2-cyclopenten-1-ol (tautomer); (S)-2-Hydroxy-5-(piperazin-1-yl)cyclopentan-1-one; 2-Cyclopenten-1-one, 5-(1-piperazinyl)-, (2S)-; 1253792-24-3; (S)-5-(Piperazin-1-yl)cyclopentan-2-one; Chiral Piperazine Cyclopentanone Derivative
EINECS	Contact for details

Quality Control

Our (2S)-2-Hydroxy-5-(Piperazin-1-Yl)Cyclopentanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) documenting identity, purity (typically >97% by HPLC), and specific impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.