Description

(S)-1-Cbz-3-Piperidineacetic Acid Methyl Ester is a high-purity chiral piperidine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a protected, enantiomerically pure scaffold for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of chiral drug candidates, especially those targeting neurological and cardiovascular diseases.
• Peptidomimetic Research: Used in the design and construction of peptide analogs and protease inhibitors due to its piperidine acetic acid backbone.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective reactions to introduce the (S)-configured piperidine moiety.
• Medicinal Chemistry: Utilized in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Agrochemical Development: Intermediate in the synthesis of novel, enantiomerically pure pesticides and herbicides.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-scale GMP batches.

Basic Information

Product Name	(S)-1-Cbz-3-Piperidineacetic Acid Methyl Ester
CAS No.	1253792-17-4
Molecular Formula	C16H21NO4
Molecular Weight	291.34 g/mol
Synonyms	Methyl (S)-1-[(benzyloxy)carbonyl]-3-piperidineacetate; (S)-1-Carbobenzoxy-3-piperidineacetic Acid Methyl Ester; (S)-1-Cbz-3-piperidylacetic Acid Methyl Ester; (S)-Methyl 1-(Cbz)-3-piperidineacetate; (S)-1-N-Cbz-3-piperidineacetic Acid Methyl Ester; (3S)-1-[(Benzyloxy)carbonyl]piperidine-3-acetic Acid Methyl Ester; (S)-1-(Benzyloxycarbonyl)piperidine-3-acetic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our (S)-1-Cbz-3-Piperidineacetic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and optical purity suitable for research and development. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.