Description

5-Chloropyridine-3-Carboxamidine is a high-purity chemical building block of significant interest in advanced organic synthesis. Its core value lies in its bifunctional structure, combining a reactive amidine group with a halogenated pyridine ring, making it a versatile precursor for constructing complex nitrogen-containing heterocycles. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Chemical Biology Probe Synthesis: Serves as a building block for creating molecular probes to study biological pathways and enzyme functions.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal catalysis and coordination chemistry.
• Heterocyclic Compound Library Synthesis: An essential starting material for generating diverse compound libraries in medicinal chemistry for high-throughput screening.

Basic Information

Product Name	5-Chloropyridine-3-Carboxamidine
CAS No.	1253792-00-5
Molecular Formula	C6H6ClN3
Molecular Weight	155.58 g/mol
Synonyms	3-Amidino-5-chloropyridine; 5-Chloro-3-pyridinecarboxamidine; 5-Chloronicotinamidine; 5-Chloro-3-amidinopyridine; 3-Cyano-5-chloropyridine amidine; 5-Chloro-pyridine-3-carboxamidine; 1253792-00-5
EINECS	Contact for details

Quality Control

Our 5-Chloropyridine-3-Carboxamidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.