Description

1-tert-Butyl 2-Methyl 1,4-Diazepane-1,2-Dicarboxylate Hydrochloride is a high-purity, protected diazepane derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceutical candidates and complex bioactive molecules. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Peptidomimetic Synthesis: Employed in the design and synthesis of peptidomimetics and constrained peptides due to its diazepane core structure.
• Chemical Biology Probes: Serves as a starting material for developing molecular probes to study biological pathways and enzyme functions.
• Process Chemistry Development: Used in route scouting and optimization for the scalable production of complex target molecules.
• Academic Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	1-tert-Butyl 2-Methyl 1,4-Diazepane-1,2-Dicarboxylate Hydrochloride
CAS No.	1253789-34-2
Molecular Formula	C13H24N2O4 • HCl
Molecular Weight	308.80 g/mol (Free base: 272.34 g/mol)
Synonyms	1-(tert-Butoxycarbonyl)-2-(methoxycarbonyl)-1,4-diazepane hydrochloride; 1-Boc-2-(COOMe)-1,4-diazepane HCl; 1,4-Diazepane-1,2-dicarboxylic acid, 1-(1,1-dimethylethyl) 2-methyl ester, hydrochloride; tert-Butyl methyl 1,4-diazepane-1,2-dicarboxylate hydrochloride; Methyl 1-(tert-butoxycarbonyl)-1,4-diazepane-2-carboxylate hydrochloride; 1-N-Boc-2-COOMe-1,4-diazepane HCl; 1253789-34-2
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 2-Methyl 1,4-Diazepane-1,2-Dicarboxylate Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.