Description

3-Pyridinamine, 2-Bromo-6-Fluoro-5-Methyl- is a high-purity halogenated pyridinamine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique substitution pattern, which provides a versatile scaffold for constructing complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors, receptor modulators, and other small-molecule therapeutics.
• Agrochemical Research: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core for bioactivity.
• Material Science Precursor: Acts as a functional monomer or ligand precursor in the development of advanced polymers, metal-organic frameworks (MOFs), and electronic materials.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a molecular probe to investigate biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Pyridinamine, 2-Bromo-6-Fluoro-5-Methyl-
CAS No.	1253654-77-1
Molecular Formula	C6H6BrFN2
Molecular Weight	205.03 g/mol
Synonyms	2-Bromo-6-fluoro-5-methylpyridin-3-amine; 5-Methyl-2-bromo-6-fluoropyridin-3-amine; 3-Amino-2-bromo-6-fluoro-5-methylpyridine; 2-Bromo-6-fluoro-5-methyl-3-pyridinamine; 2-Bromo-6-fluoro-5-methyl-3-aminopyridine
EINECS	Contact for details

Quality Control

Our production of 3-Pyridinamine, 2-Bromo-6-Fluoro-5-Methyl- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to reliable supply and traceable quality supports your R&D and scale-up processes under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.