Description

8-Bromo-1,2,3,4-tetrahydropyrido[3,4-b]pyrazine is a high-value brominated heterocyclic building block, specifically a fused pyrazine derivative, essential for advanced organic synthesis. This compound is a critical intermediate in medicinal chemistry, enabling the rapid construction of complex molecular scaffolds for drug discovery programs. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers focused on developing novel therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel bioactive molecules.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) in drug discovery.
• Chemical Biology Probes: Serves as a building block for creating molecular probes to study biological processes and protein function.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection.
• Academic Research: Used in universities and research institutes for methodological development and exploratory synthesis of novel heterocycles.

Basic Information

Product Name	8-Bromo-1,2,3,4-tetrahydropyrido[3,4-b]pyrazine
CAS No.	1253526-90-7
Molecular Formula	C7H8BrN3
Molecular Weight	214.06 g/mol
Synonyms	8-Bromo-1,2,3,4-tetrahydropyrido[3,4-b]pyrazine; 8-Bromo-3,4-dihydro-1H-pyrido[3,4-b]pyrazine; 1,2,3,4-Tetrahydropyrido[3,4-b]pyrazine, 8-bromo-; 8-Bromo-1,2,3,4-tetrahydropyrido[3,4-b]pyrazine; 8-Bromotetrahydropyrido[3,4-b]pyrazine
EINECS	Contact for details

Quality Control

Our 8-Bromo-1,2,3,4-tetrahydropyrido[3,4-b]pyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.