Description

Trifluoroacetyl Piperazine 2,2,2-Trifluoroacetate is a high-purity, advanced pharmaceutical intermediate and building block. This compound is valued for its role in introducing the trifluoroacetyl protecting group and its utility in synthesizing complex molecules with enhanced metabolic stability and lipophilicity. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Protecting Group Reagent: Used to introduce the trifluoroacetyl group in peptide and organic synthesis, offering advantageous deprotection characteristics.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Chemical Biology & Proteomics: Employed in the modification of biomolecules and as a tool compound for studying enzyme inhibition and protein interactions.
• Material Science: Potential use in the synthesis of specialty polymers and coatings that require specific fluorine-containing motifs for unique surface properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high-purity, fluorinated piperazine derivatives.

Basic Information

Product Name	Trifluoroacetyl Piperazine 2,2,2-Trifluoroacetate
CAS No.	1252780-72-5
Molecular Formula	C8H9F6N2O3
Molecular Weight	286.16 g/mol
Synonyms	1-Trifluoroacetylpiperazine Trifluoroacetate; Piperazine, 1-(trifluoroacetyl)-, 2,2,2-trifluoroacetate; 1-(Trifluoroacetyl)piperazine trifluoroacetate salt; N-Trifluoroacetylpiperazine TFA Salt; TFA Salt of Trifluoroacetylpiperazine; 2,2,2-Trifluoroacetic acid - 1-(2,2,2-trifluoroacetyl)piperazine (1:1); Trifluoroacetylpiperazine TFA
EINECS	Contact for details

Quality Control

Our Trifluoroacetyl Piperazine 2,2,2-Trifluoroacetate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring it meets the stringent requirements for pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.