Description

6-Bromo-3-Chloropicolinonitrile is a high-purity, multi-functional heterocyclic building block essential for advanced chemical synthesis. Its value lies in its unique halogenated pyridine core, which provides versatile reactivity for constructing complex molecular architectures. This compound is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the presence of bromine and chlorine leaving groups.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological pathways and target engagement.

Basic Information

Product Name	6-Bromo-3-Chloropicolinonitrile
CAS No.	1252046-16-4
Molecular Formula	C6H2BrClN2
Molecular Weight	217.45 g/mol
Synonyms	3-Chloro-6-bromopicolinonitrile; 6-Bromo-3-chloro-2-cyanopyridine; 2-Cyano-6-bromo-3-chloropyridine; 2-Pyridinecarbonitrile, 6-bromo-3-chloro-; Picolinonitrile, 6-bromo-3-chloro-; 6-Bromo-3-chloropyridine-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Chloropicolinonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the original container sealed under an inert atmosphere to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.